FILSLAN-NF // Neurofilament Assay for the Diagnosis of ALS

Topic / Pathology

  • SLA

Objectives

Primary objective : to evaluate the contribution of serum pNFH and NFL neurofilament assays in the diagnosis of ALS in a selected population of patients with progressive motor neuron disease with no definite diagnosis.

Secondary objectives :

1. To evaluate the contribution of the combined pNFH and NFL neurofilament assay in serum versus the pNFH and NFL assay alone in the diagnosis of ALS in a selected population of patients with progressive motor neuron disease without a definitive diagnosis.

2. Evaluate the contribution of the combined pNFH and NFL neurofilament assay in serum versus the clinical impression of the expert neurologist in an ALS center.

Find out morehttps://clinicaltrials.gov/ct2/show/NCT05077696

Sponsor

Assistance Publique Hôpitaux de Paris (APHP)

Investigator

National coordinator : Dr Maria Del Mar Amador

Status

Completed

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Updated on 19 December 2024